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Laboratory evaluation of a physiologic sampling pump (PSP).

Authors
Lin-MI; Groves-WA; Freivalds-A; Lee-L; Lee-EG; Slaven-JE; Harper-M
Source
J Environ Monit 2010 Jul; 12(7):1415-1421
NIOSHTIC No.
20037171
Abstract
Recently, physiologic sampling pumps (PSPs), which can adjust their sampling rates in proportion to wearers' minute ventilation ((V) over dot(E)), have been proposed to better estimate exposure to airborne contaminants in the workplace. A laboratory evaluation was conducted to compare the performance of a new PSP with a traditional sampling pump (TSP) in an exposure chamber. Fifteen subjects (aged 19-36 years) performed two replicate sessions of step-tests for correlated and uncorrelated exposure scenarios on four separate days. When exposed to a scenario in which subject ((V) over dot(E)) is highly correlated with m-xylene concentration over the sampling period (r = 0.93), the PSP-measured time-weighted average (TWA) concentrations are higher than TSP-measured concentrations (average ratio of PSP to TSP = 1.18). The ratio of PSP- and TSP-measured TWA concentrations for the uncorrelated scenario (r = 0.02) is closer to one, as expected, with an average value of 0.94. The test results of the linear mixed model further indicate that the performance of the PSP is unaffected by the anthropometric and physiological characteristics of the wearer. Potential differences in exposure estimates resulting from the use of the two instruments were examined in light of various schemes which can potentially occur in the field. With the capability of estimating the total volume of air inhaled over the sampling period with improved accuracy, PSPs show promise in reducing the inherent uncertainty in current risk assessment approaches that entail constant-flow (TSP) sampling approaches.
Keywords
Age-groups; Air-sampling; Analytical-methods; Biochemical-analysis; Biological-effects; Biological-factors; Biological-monitoring; Breathing-zone; Exposure-assessment; Exposure-levels; Exposure-methods; Inhalation-studies; Laboratory-testing; Particulates; Physiological-effects; Physiological-factors; Physiological-measurements; Physiological-response; Physiological-testing; Pumps; Risk-analysis; Statistical-analysis
Contact
Ming-I (Brandon) Lin, The National Cheng Kung University, Tainan, Taiwan, 701
CODEN
JEMOFW
Publication Date
20100701
Document Type
Journal Article
Email Address
brandonl@mail.ncku.edu.tw
Fiscal Year
2010
NTIS Accession No.
NTIS Price
Issue of Publication
7
ISSN
1464-0325
NIOSH Division
HELD
Source Name
Journal of Environmental Monitoring
State
WV; PA
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