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Urinary 1-hydroxypyrene levels in offshore workers.

Authors
Hopf-NB; Kirkeleit-J; Kramer-SL; Moen-B; Succop-P; Genter-MB; Carreón-T; Mack-J; Talaska-G
Source
Int Arch Occup Environ Health 2010 Jan; 83(1):55-59
NIOSHTIC No.
20037083
Abstract
Objectives: To compare differences in pre- and post-shift urinary 1-hydroxypyrene (1OHP) levels as a measure of internal dose of polycyclic aromatic hydrocarbons (PAHs) between two groups of oil production workers offshore assumed to be exposed to PAH, and to compare the exposed group to an unexposed control group. Methods: Participants' (n = 42) urine samples, collected over a study period of three consecutive 12-h work days (pre-shift on the first day and post-shift on the third day), were analyzed using high performance liquid chromatography (HPLC) with fluorescence detection. Analysis of covariance was used in the statistical models. Results: (1) Post-shift 1OHP levels were significantly higher in the exposed workers compared to the controls. (2) Tank workers and process operators did not show statistically significant different post-shift 1OHP levels. Conclusion: Altogether, this study indicates the presence of a low level PAH exposure among offshore oil production workers.
Keywords
Biological-monitoring; Polychlorinated-aromatic-hydrocarbons; Oil-industry; Humans; Urinalysis; Author Keywords: Polycyclic aromatic hydrocarbons; PAH; 1-Hydroxypyrene; Offshore; Biological monitoring; Crude oil exposure
CODEN
IAEHDW
Publication Date
20100101
Document Type
Journal Article
Email Address
NancyBHopf@gmail.com
Funding Type
Grant
Fiscal Year
2010
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-T42-OH-008432
Issue of Publication
1
ISSN
0340-0131
Source Name
International Archives of Occupational and Environmental Health
State
OH
Performing Organization
University of Cincinnati
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