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Cigarette smoking and pulmonary diffusing capacity.

Authors
Van Ganse-WF; Ferris-BG Jr.; Cotes-JE
Source
Am Rev Respir Dis 1972 Jan; 105(1):30-41
NIOSHTIC No.
20036824
Abstract
Cigarette smoking caused a reduction in the diffusing capacity of the lungs for carbon monoxide and a reduction in coefficient of diffusion of carbon monoxide. This implies that cigarette smoking should be considered in prediction equations. The reduction in the diffusing capacity appeared to be due to a change in the volume of blood in the capillaries. This could account for some of the reversible changes observed in ex-cigarette smokers. The membrane component changed more with age. Prediction formulas were developed for diffusing capacity for the ratio, diffusing capacity/alveolar volume, based on age, height, and life-time packs smoked.
Keywords
Age-factors; Biological-effects; Blood-samples; Blood-serum; Cigarette-smoking; Humans; Mathematical-models; Men; Pulmonary-disorders; Pulmonary-function-tests; Pulmonary-system; Pulmonary-system-disorders; Respiration; Respiratory-function-tests; Respiratory-system-disorders; Spirometry; Vital-capacity; Women
CODEN
ARDSBL
CAS No.
630-08-0
Publication Date
19720101
Document Type
Journal Article
Funding Amount
146424
Funding Type
Grant
Fiscal Year
1972
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-000310
Issue of Publication
1
ISSN
0003-0805
Priority Area
Pulmonary-system-disorders
Source Name
American Review of Respiratory Disease
State
MA
Performing Organization
Harvard University, Boston, Massachusetts
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