Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

NIOSHTIC-2 Publications Search

Search Results

Allergen content of patient problem and nonproblem gloves: relationship to allergen-specific patch-test findings.

Authors
Siegel-PD; Fowler-JF Jr.; Storrs-FJ; Sasseville-D; Pratt-M; Bledsoe-TA; Law-BF; Beezhold-D; Zug-K; Fowler-LM
Source
Dermatitis 2010 Mar; 21(2):77-83
NIOSHTIC No.
20036680
Abstract
BACKGROUND: Identification of putative contact allergen and source material is often done by a combination of patch testing and manufacturer-supplied product information. The accuracy of the identification of allergen-source material and level of allergen in that allergen-source material is not known. OBJECTIVE: The objectives of the study were to survey the chemical allergen content of glove allergic contact dermatitis (ACD) patient-identified problem and nonproblem gloves and to evaluate the ability of the patient to discriminate between problem and nonproblem gloves. METHODS: Gloves from patch-tested rubber allergen-positive ACD patients were analyzed for species and amount of rubber allergen. RESULTS: Approximately half the subjects were able to correctly identify their problem and nonproblem gloves. Correct association of a glove with ACD was directly related to patch-test reaction severity and inversely related to the number of glove brands being used by the patient. Of note, thiurams were not detected in any of the gloves examined. CONCLUSIONS: Although patch testing is invaluable in identifying individual allergen sensitivities, the identification of the ACD-causative specific chemical allergen and source material remains problematic. All glove brands used within days prior to and during an ACD episode should be considered potential sources of the contact allergen.
Keywords
Contact-allergies; Gloves; Allergic-reactions; Allergies; Allergic-disorders; Allergens
Publication Date
20100301
Document Type
Journal Article
Funding Type
Grant
Fiscal Year
2010
NTIS Accession No.
NTIS Price
Issue of Publication
2
ISSN
1710-3568
NIOSH Division
HELD
Source Name
Dermatitis
State
WV; KY; NH
TOP