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Peripheral and central auditory dysfunction induced by occupational exposure to organic solvents.

Authors
Fuente-A; Slade-MD; Taylor-T; Morata-TC; Keith-RW; Sparer-J; Rabinowitz-PM
Source
J Occup Environ Med 2009 Oct; 51(10):1202-1211
NIOSHTIC No.
20035985
Abstract
Objective: To examine the effects of solvent exposure on hearing function, through an audiological test battery, in a population not occupationally exposed to high levels of noise. Methods: One hundred ten workers from a coating factory were studied. Jobs at the factory were divided into three different levels of solvent exposure. Hearing status was assessed with a test battery including pure-tone hearing thresholds (0.5-8 kHz), high-frequency hearing thresholds (12 and 16 kHz), and dichotic listening measured through dichotic digits test. Multiple linear regression models were created to explore possible association between solvent exposure and each of the hearing outcomes. Results: Significant associations between solvent exposure and the three hearing outcomes were found. Covariates such as age, gender, race, and ethnicity were also significantly associated with the studied hearing outcomes. Conclusions: Occupational exposure to solvents may induce both peripheral and central auditory dysfunction. The dichotic digits test seems as a sensible tool to detect central auditory dysfunction associated with solvent exposure. Hearing loss prevention programs may use this tool to monitor hearing in solvent-exposed workers.
Keywords
Audiological-testing; Auditory-system; Biochemical-indicators; Biochemistry; Biological-effects; Biological-factors; Biological-systems; Chemical-factory-workers; Chemical-hypersensitivity; Chemical-reactions; Demographic-characteristics; Exposure-assessment; Exposure-levels; Exposure-methods; Health-hazards; Hearing-disorders; Hearing-loss; Medical-monitoring; Occupational-exposure; Occupational-health; Physiological-effects; Risk-factors; Solvents; Statistical-analysis; Worker-health
Contact
Adrian Fuente, PhD, Escuela de Fonoaudiologia, Facultad de Medicina, Universidad de Chile, Independencia 1027
CODEN
JOEMFM
Publication Date
20091001
Document Type
Journal Article
Email Address
afuente@med.uchile.cl
Fiscal Year
2010
NTIS Accession No.
NTIS Price
Issue of Publication
10
ISSN
1076-2752
NIOSH Division
DART
Source Name
Journal of Occupational and Environmental Medicine
State
OH
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