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Evaluation of respiratory and skin problems.

Authors
Cummings-KJ; Boylstein-RJ; Cox-Ganser-J
Source
Int J Occup Environ Health 2009 Apr; 15(2):230
NIOSHTIC No.
20035665
Abstract
The HHE Program responded to a request from machine shop workers in a facility that produces aluminum wheels. Workers reported recurrent pneumonias, asthma, and other symptoms that they related to metalworking fluid (MWF). HHE Program investigators conducted phone interviews with workers, company officials, and treating physicians. Investigators reviewed medical records and records of MWF and air monitoring. They also analyzed samples of the MWF using culture, endotoxin and fungal glucan assays, and polymerase chain reaction for mycobacterial DNA. Investigators found that some workers had work-related respiratory and skin problems, including occupational asthma and a constellation of symptoms concerning for hypersensitivity pneumonitis. Monitoring records demonstrated air levels of MWF above the NIOSH recommended exposure limit and no or IQW detection of bacteria and fungi in MWF. Culture of MWF showed minimal bacterial growth and no mycobacterial or fungal growth. Endotoxin levels were very low (52-150 ED/ml), but glucan levels were detectable (133-266 ng/ml). Nearly all (11/12) samples had mycobacterial DNA, specifically M. immunogenum. Negative MWF cultures do not preclude the occurrence of MWF-related symptoms. Non-culture analytic methods can provide useful information about microbial presence in MWF. The final report is available at https://www.cdc.gov/niosh/hhe/reports/pdfs/2007-0263-3069.pdf.
Keywords
Region-7; Metalworking-industry; Metalworking-fluids; Metalworking; Respiratory-system-disorders; Bronchial-asthma; Pulmonary-system-disorders; Pulmonary-function; Hypersensitivity; Dermatitis; Dermatosis; Mycotoxins; Bacteria; Skin-disorders; Skin-irritants; Author Keywords: metalworking fluid; occupational asthma; hypersensitivity pneumonitis; dermatitis; mycobacteria
CODEN
IOEHFU
Publication Date
20090401
Document Type
Abstract
Fiscal Year
2009
NTIS Accession No.
NTIS Price
Issue of Publication
2
ISSN
1077-3525
NIOSH Division
DRDS
Source Name
International Journal of Occupational and Environmental Health
State
OH; KS
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