Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

NIOSHTIC-2 Publications Search

Search Results

Cross-talk between lung and systemic circulation during carbon nanotube respiratory exposure. Potential biomarkers.

Authors
Erdely-A; Hulderman-T; Salmen-R; Liston-A; Zeidler-Erdely-PC; Schwegler-Berry-D; Castranova-V; Koyama-S; Kim-YA; Endo-M; Simeonova-PP
Source
Nano Lett 2009 Jan; 9(1):36-43
NIOSHTIC No.
20034966
Abstract
Nanotechnology is an emerging field that demands urgent development of adequate toxicology and risk assessment. The previous experimental data on carbon nanotube respiratory exposure strongly suggest the need for complex evaluation of potential toxicity. Our work demonstrates that after carbon nanotube deposition in the lung, acute local and systemic responses are activated and characterized by a blood gene and protein expression signature. The approach described here will foster the development of biomarkers for application in human screening of nanoparticle exposure.
Keywords
Biomarkers; Genes; Respirable-dust; Respiratory-system-disorders; Pulmonary-system-disorders; Nanotechnology
CODEN
NALEFD
Publication Date
20090101
Document Type
Journal Article
Email Address
Psimeonova@cdc.gov
Fiscal Year
2009
NTIS Accession No.
NTIS Price
Issue of Publication
1
ISSN
1530-6984
NIOSH Division
HELD
Source Name
Nano Letters
State
WV
TOP