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Ah receptor: xenobiotic response meets inflammation.

Authors
Ma-Q
Source
Blood 2008 Aug; 112(4):928-929
NIOSHTIC No.
20034328
Abstract
AhR mediates a broad range of biological responses to environmental chemicals, including suppression of immune functions. In this issue of Blood, Lawrence and colleagues demonstrate that AhR is responsible for the anti-inflammatory activity of new antiallergic drug candidates, likely by blocking dendritic-cell function to generate proinflammatory T-helper cells.
Keywords
Biological-effects; Biological-monitoring; Biological-systems; Environmental-exposure; Environmental-hazards; Cell-biology; Cell-function; Cellular-function; Cellular-reactions; Chemical-hypersensitivity; Chemical-properties; Allergic-reactions; Drug-receptor; Drugs; Immune-system; Immunochemistry
Contact
Health Effects Laboratory Division, CDC National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV, 26505
CODEN
BLOOAW
CAS No.
1746-01-6
Publication Date
20080815
Document Type
Other
Fiscal Year
2008
NTIS Accession No.
NTIS Price
Issue of Publication
4
ISSN
0006-4971
NIOSH Division
HELD
Source Name
Blood
State
WV
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