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Characteristics of aerosols generated during a cough.

Authors
Frazer-DG; Goldsmith-WT; Afshari-AA; Philips-N; Weber-KC; Petsonk-EL
Source
FASEB J 1997 Feb; 11(3):A348
NIOSHTIC No.
20033993
Abstract
A system including a spirometer and LAS-X particle analyzer was designed to examine aerosols generated during a cough. The system was held at 37C in a temperature controlled chamber. Air was pulled through a HEPA filter and the spirometer at a constant rate (5 l/min) so that aerosols introduced to the spirometer-aerosol analyzer system were continuously washed out. A subject breathing ambient air coughed into the spirometer, then breathed HEPA filtered air and coughed at 2 min intervals for 6 min. Background aerosol measurements were recorded prior to each cough. Preliminary experiments showed that the difference in the number of particles recovered from the spirometer with respect to background (NPD) was greatest following the first cough, was reduced during the second cough, but tended to increase following the third and four1h coughs. Particle diameters ranged between 0.1 and 5.0 micro m after each cough, and more that 95% of the particles had diameters less than 1.0 micro m. Results also showed that there was a significant variation in NPD (+/-300%) between subjects following each of the four coughs.
Keywords
Inhalation-studies; Spirometry; Particle-counters; Particulates; Aerosol-particles; Lung-function; Breathing
CODEN
FAJOEC
Publication Date
19970228
Document Type
Abstract; Conference/Symposia Proceedings
Fiscal Year
1997
NTIS Accession No.
NTIS Price
Issue of Publication
3
ISSN
0892-6638
NIOSH Division
HELD; DRDS
Source Name
The FASEB Journal
State
WV
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