Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

NIOSHTIC-2 Publications Search

Search Results

Pesticide use and chronic bronchitis among farmers in the agricultural health study.

Authors
Hoppin-JA; Valcin-M; Henneberger-PK; Kullman-GJ; Umbach-DM; London-SJ; Alavanja-MCR; Sandler-DP
Source
Am J Ind Med 2007 Dec; 50(12):969-979
NIOSHTIC No.
20033662
Abstract
Background: Farmers have increased risk for chronic bronchitis. Few investigators have considered pesticides. Methods: We evaluated pesticides as risk factors for chronic bronchitis using the Agricultural Health Study enrollment data on lifetime pesticide use and history of doctor-diagnosed chronic bronchitis from 20,908 private pesticide applicators, primarily farmers. Results: A total of 654 farmers (3%) reported chronic bronchitis diagnosed after age 19. After adjustment for correlated pesticides as well as confounders, 11 pesticides were significantly associated with chronic bronchitis. Heptachlor use had the highest odds ratio (OR=1.50, 95% Confidence Interval (CI)=1.19, 1.89). Increased prevalence for chronic bronchitis was also seen for individuals who had a history of a high pesticide exposure event (OR=1.85, 95% CI=1.51, 2.25) and for those who also applied pesticides in off-farm jobs (OR=1.40, 95%CI=1.04, 1.88). Co-morbid asthma and current farm activities did not explain these results. Conclusions: These results provide preliminary evidence that pesticide use may increase chronic bronchitis prevalence.
Keywords
Occupational-exposure; Agricultural-chemicals; Agricultural-workers; Pesticides; Pesticides-and-agricultural-chemicals; Respiratory-system-disorders; Risk-analysis; Risk-factors; Farmers; Pulmonary-system-disorders; Lung-disorders; Lung-irritants; Chronic-inflammation; Bronchial-asthma; Statistical-analysis; Herbicides; Insecticides; Organo-chlorine-compounds; Organo-phosphorus-pesticides; Pyrethroids; Fumigants; Fungicides
Contact
Jane Hoppin, NIEHS, Epidemiology Branch, MD A3-05, P.O. Box 12233, ResearchTriangle Park, NC 27709-2233
CODEN
AJIMD8
CAS No.
76-44-8
Publication Date
20071201
Document Type
Journal Article
Email Address
hoppin1@niehs.nih.gov
Fiscal Year
2008
NTIS Accession No.
NTIS Price
Issue of Publication
12
ISSN
0271-3586
NIOSH Division
DRDS
Priority Area
Agriculture, Forestry and Fishing
Source Name
American Journal of Industrial Medicine
State
MD; NC; WV
TOP