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Human health implications of nanomaterial exposure.

Authors
Papp-T; Schiffmann-D; Weiss-D; Castranova-V; Vallyathan-V; Rahman-Q
Source
Nanotoxicology 2008 Mar; 2(1):9-27
NIOSHTIC No.
20033534
Abstract
Nanotechnology presents countless opportunities to develop new and improved consumer products for the benefit of society. However, as the industrial production and use of nanotechnology products continue to expand at a fast scale, potential human health concerns and ecological safeguards for the environment need to be addressed. Health risk assessment involving different animal species for multi-organ toxicity complimented with molecular investigations in cells is essential for investigating the potential toxic effects of nanomaterials. The purpose of this review is to present the current state of knowledge regarding the potential routes of human exposure to nanomaterials and their biological health effects. Although anthropogenic nanosized particles emitted in the environment are known to produce adverse human health in susceptible populations, much remains to be explored. Exposures can occur from direct exposure or from the use of commercial products made of nanomaterials. Safe manufacturing guidelines for prevention of exposures and recommendations on safe handling and use need to be established on a proactive basis to prevent adverse outcomes.
Keywords
Humans; Health-hazards; Toxic-effects; Airborne-dusts; Airborne-particles; Nanotechnology
Publication Date
20080301
Document Type
Journal Article
Email Address
vav1@cdc.gov
Fiscal Year
2008
NTIS Accession No.
NTIS Price
ISSN
1743-5390
NIOSH Division
HELD
Priority Area
Manufacturing
Source Name
Nanotoxicology
State
WV
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