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How to determine the permeability for cement infiltration of osteoporotic cancellous bone.

Authors
Baroud-G; Wub-JZ; Bohner-M; Sponagel-S; Steffen-T
Source
Med Eng Phys 2003 May; 25(4):283-288
NIOSHTIC No.
20032640
Abstract
Cement augmentation is an emerging surgical procedure in which bone cement is used to infiltrate and reinforce osteoporotic vertebrae. Although this infiltration procedure has been widely applied, it is performed empirically and little is known about the flow characteristics of cement during the injection process. We present a theoretical and experimental approach to investigate the intertrabecular bone permeability during the infiltration procedure. The cement permeability was considered to be dependent on time, bone porosity, and cement viscosity in our analysis. In order to determine the time-dependent permeability, ten cancellous bone cores were harvested from osteoporotic vertebrae, infiltrated with acrylic cement at a constant flow rate, and the pressure drop across the cores during the infiltration was measured. The viscosity dependence of the permeability was determined based on published experimental data. The theoretical model for the permeability as a function of bone porosity and time was then fit to the testing data. Our findings suggest that the intertrabecular bone permeability depends strongly on time. For instance, the initial permeability (60.89 mm4/N*s) reduced to approximately 63% of its original value within 18 seconds. This study is the first to analyze cement flow through osteoporotic bone. The theoretical and experimental models provided in this paper are generic. Thus, they can be used to systematically study and optimize the infiltration process for clinical practice.
Keywords
Surgery; Bone-structure; Osteogenesis; Viscosity; Porous-materials; Bone-disorders
Contact
McGill University, Orthopaedic Research Laboratory, Royal Victoria Hospital, 687 Pine Avenue West, Montreal, QC HAS 1A1, Canada
CODEN
MEPHEO
Publication Date
20030501
Document Type
Journal Article
Fiscal Year
2003
NTIS Accession No.
NTIS Price
Issue of Publication
4
ISSN
1350-4533
NIOSH Division
HELD
Source Name
Medical Engineering & Physics
State
WV
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