Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

NIOSHTIC-2 Publications Search

Search Results

Correlation between the content of intermediate chain-length fatty acids and copper in the milk of Fulani women.

Authors
Shores-JT; VanderJagt-DJ; Millson-M; Huang-YS; Glew-RH
Source
Prostaglandins, Leukot Essent Fat Acids 2000 Oct; 63(4):203-207
NIOSHTIC No.
20032335
Abstract
Intermediate chain-length fatty acids (C10-C14) in human milk triglycerides provide an easily absorbable fuel that provide a significant amount of the energy needed for growth during the first few months of life. The C10-C14 fatty acid and trace mineral content of human milk is variable. In this report we examined the relationship between the content of calcium, copper, magnesium, manganese, phosphorus, and zinc, and the weight percentage of C10-C14 fatty acids in milk from 33 Fulani women in northern Nigeria between 2 and 24 weeks post-gestation. The milk from these women contained proportions of C10-C14 fatty acids that were comparable to those reported for other populations around the world, as were the concentrations of Ca, Cu, Mg, Mn, Zn and P. Significant correlations were observed between the milk content of Cu and the wt% of C10 (P=0. 005, r=0.475), C12 (P=0.001, r=0.539), C14 (P=0.44, r=0.352) and the total intermediate chain-length fatty acids (P=0.008, r=0.450). No correlations were observed between these fatty acids and any of the other five minerals. We speculate that the relationship between Cu and fatty acids could be related to a requirement for Cu by an enzyme required for C10-C14 fatty acid biosynthesis (e.g. decanoyl deacylase) in mammary tissue, or to some unique Cu binding properties of the intermediate chain length fatty acids.
Keywords
Physiological-factors; Humans; Human-factors-engineering; Women; Energy-metabolism; Growth-factors; Fat-metabolism
Contact
Robert H. Glew, PhD, Department of Biochemistry and Molecular Biology, School of Medicine, University of New Mexico School of Medicine, Albuquerque, New Mexico 87131
CODEN
PLEAEU
Publication Date
20001001
Document Type
Journal Article
Email Address
rglew@salud.unm.edu
Fiscal Year
2001
NTIS Accession No.
NTIS Price
Issue of Publication
4
ISSN
0952-3278
NIOSH Division
DART
Source Name
Prostaglandins, Leukotrienes, and Essential Fatty Acids
State
OH; NM
TOP