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Pulmonary effects of single-walled carbon nanotubes: inflammatory response, oxidative stress/signaling, and recognition by macrophages.

Authors
Kagan-VE; Rao-KMK; Kisin-ER; Young-S-H; Meighan-T; Murray-AR; Tyurina-YY; Castranova-V; Shvedova-AA
Source
Nanotechnology - Toxicological Issues and Environmental Safety (NATO Science for Peace and Security Series / NATO Science for Peace and Security Series C: Environmental Security). Simeonova PP, Opopol N, Luster MI. eds., Dordrecht, The Netherlands: Springer, 2007 May; :65-75
NIOSHTIC No.
20032331
Abstract
Nanosized materiaols and nano-scaled processes are believed to be beneficial for many industries as well as for medicine. However, irrational unjustified use of nanomaterials may also pose risks to human health and the environment, particularly single-walled carbon nanotubes, such as their decytotoxid effects, their ability to cause an inflammatory response, and induction of oxidative stress. Further, recognigion and engulfment of nanotubes in tissue and circulation are discussed. Possible involvement of lung fibroblast pulmonary responses to nanotubes are considered.
Keywords
Aerosols; Aerosol-particles; Airborne-particles; Airborne-fibers; Toxicology; Nanotechnology
Contact
Pathology/Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505
Publication Date
20070515
Document Type
Book or book chapter
Editors
Simeonova-PP; Opopol-N; Luster-MI
Fiscal Year
2007
NTIS Accession No.
NTIS Price
ISBN No.
9781402060755
NIOSH Division
HELD
Priority Area
Manufacturing
Source Name
Nanotechnology - Toxicological Issues and Environmental Safety (NATO Science for Peace and Security Series / NATO Science for Peace and Security Series C: Environmental Security)
State
WV; PA
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