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Fatal rat-bite fever --- Florida and Washington, 2003.

Authors
Pollock-WJ; Cunningham-R; Lanza-J; Buck-S; Williams-PA; Hamilton-JJ; Sanderson-R; Selove-D; Harper-T; Yu-DT; Leslie-M; Hofmann-J; Reagan-S; Fischer-M; Whitney-A; Sacchi-C; Levett-P; Daneshvar-M; Helsel-L; Morey-R; Zaki-S; Paddock-C; Shieh-W; Sumner-J; Guarner-J; Gross-D
Source
MMWR 2005 Jan; 53(51&52):1197-1202
NIOSHTIC No.
20031831
Abstract
Rat-bite fever (RBF) is a rare, systemic illness caused by infection with Streptobacillus moniliformis. RBF has a case-fatality rate of 7%--10% among untreated patients (1). S. moniliformis is commonly found in the nasal and oropharyngeal flora of rats. Human infection can result from a bite or scratch from an infected or colonized rat, handling of an infected rat, or ingestion of food or water contaminated with infected rat excreta (1). An abrupt onset of fever, myalgias, arthralgias, vomiting, and headache typically occurs within 2--10 days of exposure and is usually followed by a maculopapular rash on the extremities (1). This report summarizes the clinical course and exposure history of two rapidly fatal cases of RBF identified by the CDC Unexplained Deaths and Critical Illnesses (UNEX) Project in 2003. These cases underscore the importance of 1) including RBF in the differential diagnoses of acutely ill patients with reported rat exposures and 2) preventing zoonotic infections among persons with occupational or recreational exposure to rats.
Keywords
Zoonoses; Infectious-diseases; Microorganisms; Animals; Bacteria; Bacterial-disease; Bacterial-infections; Retail-workers
CODEN
MMWRB6
Publication Date
20050107
Document Type
Journal Article
Fiscal Year
2005
NTIS Accession No.
NTIS Price
Issue of Publication
51&52
ISSN
0892-3787
NIOSH Division
OD
Source Name
Morbidity and Mortality Weekly Report
State
WA; FL; GA
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