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Modeling dermal exposure--an illustration for spray painting applications.

Authors
Flynn-MR; Koto-Y; Fent-K; Nylander-French-LA
Source
J Occup Environ Hyg 2006 Sep; 3(9):475-480
NIOSHTIC No.
20031380
Abstract
This article presents a conceptual, mathematical model of dermal exposure resulting from aerosol deposition on human forearm hair. The model is applicable to exposure scenarios where dermal deposition is governed by aerosol impaction, interception, and diffusion mechanisms. The model employs filtration theory, single fiber efficiency equations, and a modified potential airflow approximation. The results are extended, using previously published results, for application to dermal deposition on the forearm during spray painting. The average (N = 8) predicted dermal deposition of 1,6-hexamethylene diisocyanate as collected on a 10-cm(2) tape strip is 108.9 (+/- 70.3) pmol, whereas field measurements indicated an average of 168.6 (+/- 82.0) pmol per strip. The corresponding measured average dermal flux was 3.63 pg/cm(2)s (+/- 1.34); the prediction was 2.24 pg/cm(2)sec (+/- 1.25). The study calls attention to the importance of body hair both for modeling and measuring dermal exposures.
Keywords
Models; Spray-painting; Paint-spraying; Painting; Paints; Aerosols; Aerosol-particles; Exposure-levels; Exposure-assessment; Isocyanates; Mathematical-models; Air-flow; Occupational-exposure; Cyanates; Automotive-industry; Environmental-health-monitoring; Pollutants
CODEN
JOEHA2
Publication Date
20060901
Document Type
Journal Article
Email Address
mflynn@email.unc.edu
Funding Type
Grant
Fiscal Year
2006
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-007598
Issue of Publication
9
ISSN
1545-9624
Source Name
Journal of Occupational and Environmental Hygiene
State
NC
Performing Organization
University of North Carolina, Chapel Hill, North Carolina
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