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Determination of hexamethylene diisocyanate-based isocyanates in spray-painting operations. Part 2. Comparison of high performance liquid chromatography with capillary zone electrophoresis.

Authors
Rudzinski-WE; Yin-J; England-E; Carlton-G
Source
Analyst 1999 Feb; 124(2):119-123
NIOSHTIC No.
20031349
Abstract
A capillary zone electrophoresis (CZE) approach was developed for the determination of hexamethylene diisocyanate (HDI) monomer and HDI-based oligomers. A comparison of CZE with high performance liquid chromatography (HPLC) indicates that the CZE separation completely isolates isocyanates from excess solvent, derivatizing reagent and pigment while offering a fivefold increase in sensitivity. The CZE approach allows for the quantification of HDI monomer and oligomer within a 1 min time window under the run conditions selected. For the determination of HDI-based oligomer, provided that the relative response with respect to HDI monomer is calculated, there is no significant difference (p < 0.05, n = 10) in the isocyanate air concentration when using either HPLC or CZE. The results are significant because they indicate that CZE has advantages for the determination of both HDI-based oligomer and HDI monomer generated during spray-painting operations.
Keywords
Isocyanates; Spray-painting; Paint-spraying; Samplers; Sampling; Sampling-methods; Painting; Paints; Cyanates; Pollutants; Airborne-particles; Exposure-assessment; Chromatographic-analysis
Contact
Department of Chemistry, Southwest Texas State University, San Marcos 78666
CODEN
ANALAO
CAS No.
822-06-0
Publication Date
19990201
Document Type
Journal Article
Funding Amount
88710
Funding Type
Grant
Fiscal Year
1999
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-003295
Issue of Publication
2
ISSN
0003-2654
Priority Area
Research Tools and Approaches: Exposure Assessment Methods
Source Name
Analyst
State
TX
Performing Organization
Southwest Texas State University, Department of Chemistry, San Marcos, Texas
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