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Organophosphorus pesticide urinary metabolite levels of children in farmworker households in eastern North Carolina.

Authors
Arcury-TA; Grzywacz-JG; Davis-SW; Barr-DB; Quandt-SA
Source
Am J Ind Med 2006 Sep; 49(9):751-760
NIOSHTIC No.
20031333
Abstract
BACKGROUND: Organophosphorus (OP) pesticide urinary metabolite levels in a sample of farmworker children in North Carolina are documented and compared to national reference data. The relative importance of para-occupational, residential, and environment risk factors are delineated. METHODS: Urine samples were collected from 60 farmworker children 1-6 years of age, and interviews were completed by their mothers. Urine samples were analyzed for the dialkylphosphate (DAP) metabolites of OP pesticides. Summed molar concentrations of the diethyl and dimethyl DAP metabolites provided summary measures. RESULTS: The farmworker children had relatively high levels of OP pesticide urinary metabolites compared to national reference data; for example, participating children had higher geometric means for diethylphosphate (DEP), diethylthiophosphate (DETP), and the summed diethyl metabolites. However, analyses found no pattern of significant associations between predictors and metabolite levels. CONCLUSIONS: Future research requires greater precision in sampling and measurement to determine the risk factors for pesticide exposure among farmworker children.
Keywords
Pesticides; Pesticides-and-agricultural-chemicals; Agriculture; Agricultural-industry; Agricultural-workers; Agricultural-chemicals; Occupational-exposure; Occupational-health; Environmental-health; Risk-factors; Risk-analysis; Farmers; Education; Children
Contact
Thomas A. Arcury, Department of Family and Community Medicine, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1084
CODEN
AJIMD8
Publication Date
20060101
Document Type
Journal Article
Email Address
tarcury@wfubmc.edu
Funding Type
Grant
Fiscal Year
2006
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R25-OH-007611
Issue of Publication
9
ISSN
0271-3586
Source Name
American Journal of Industrial Medicine
State
NC
Performing Organization
Wake Forest University
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