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Airway responses in healthy and asthmatic subjects following exposure to low ambient air temperature.

Authors
Zuskin-E; Schachter-EN; Mustajbegovic-J
Source
Acta Med Croatica 1996 Jan; 50(2):97-101
Link
NIOSHTIC No.
20031101
Abstract
Ventilatory capacity following exposure to low ambient air temperature (-5 degrees C) was measured in 46 male and 37 female medical students. In healthy subjects there was an increase in all test parameters during a four-hour exposure as compared to preexposure values. However, six students with bronchial asthma showed a decrease in ventilatory capacity tests following exposure to low temperature. The changes in healthy subjects as well as in asthmatics were most pronounced for the maximal flow rates at 50% and the last 25% of the vital capacity (FEF50, FEF25). The mean increase in FEF25 for healthy subjects was recorded up to a +15.1% and +6.4% increase in nonsmokers and smokers, respectively. In asthmatics, the largest decrease of FEF25 was -21.5%. Authors' data indicated that environmental exposure to low ambient air temperature caused an increase of ventilatory function tests in healthy subjects and a decrease in asthmatics, particularly in flow rates at lower lung volumes.
Keywords
Bronchial-asthma; Diseases; Temperature-effects; Exposure-assessment; Air-temperature; Exposure-levels; Smoking
CODEN
AMCREF
Publication Date
19960101
Document Type
Journal Article
Funding Amount
709316
Funding Type
Grant
Fiscal Year
1996
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-002593
Issue of Publication
2
ISSN
1330-0164
Priority Area
Pulmonary-system-disorders
Source Name
Acta Medica Croatica
State
NY
Performing Organization
Mount Sinai School of Medicine, New York, New York
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