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Review of presentations.

Lloyd-JW; Wagoner-JK; Lemen-RA; Young-R
Proceedings of NIOSH Styrene-Butadiene Briefing, April 30, 1976, Covington, Kentucky. Cincinnati, OH: NIOSH, 1976 Apr; :19-21
While we are waiting for Dr. Wagoner, I would like to summarize what we have done in the first part of this session. The mortality experience at the B. F. Goodrich Plant at Port Neches indicated a much higher leukemia mortality than you would expect, not only on the basis of the rates for the State of Texas or for the United States, but for that county where there is an excess of leukemia. At an adjacent plant, Texas-U.S. Chemical, an excess of leukemia was also observed. Following that observation, NIOSH looked for other information on the question and, specifically, they wrote to the companies and .asked them to come here and present whatever information they had. One of the first sources of information was the University of North Carolina; in particular, their report in the March (1976) issue of the Journal of Occupational Medicine presenting their observations on a six-fold excess of leukemia and lymphoma in people working in synthetic rubber at a styrene-butadiene plant. You heard the three cases of leukemia and lymphoma described and you also were told that some of these people had exposure in their history to agents that might be suspected of being leukemogenic. Nobody has denied that they might have such an exposure - they did cluster people who worked in synthetic rubber plants. Subsequent to that report the North Carolina group, reviewed their study at another styrene-butadiene plant, where they had not noticed any excess of leukemia. They noted in this review of the plant study four cases of leukemia who would have at some time worked in an area where they could have had exposure where styrene-butadiene rubber was made. The relative risk in that area was estimated to be 1.5 and that means that the rate based on some comparison was fifty per cent greater than expected with those small numbers. What we have at this point is two plants in Texas where the leukemia rate is out of line, another plant in the State of Ohio where we have recorded excess amounts of leukemia and lymphomas, and another plant where the rate appears to be in excess. A great deal still has to be worked out on this: We need to know what are the specific chemicals that these people are exposed to and we need much more detail on the process or the processes that are being used and that is why I have invited you people here. We hope you can tell us much more about this problem. I will now turn this back to Dr. Wagoner.
Cancer; Cancer-rates; Mortality-data; Mortality-rates; Rubber-manufacturing-industry; Rubber-workers; Styrenes; Styrene-butadiene-resins; Styrene-resins; Butadienes; Occupational-health; Occupational-hazards; Occupational-exposure; Occupational-diseases; Health-hazards; Risk-factors; Risk-analysis
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Proceedings of NIOSH Styrene-Butadiene Briefing, April 30, 1976, Covington, Kentucky