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Mortality of workers employed in shoe manufacturing: an update.

Authors
Lehman-EJ; Hein-MJ
Source
Am J Ind Med 2006 Jul; 49(7):535-546
NIOSHTIC No.
20030502
Abstract
In the late 1970s, the National Institute for Occupational Safety and Health identified two shoe manufacturing facilities where workers experienced relatively "pure" exposures to toluene. A mortality study was conducted through December 31, 1982. An original study did not detect elevated leukemia mortality but did detect increased lung cancer mortality. The present study is an update of the mortality of the original cohort. The study cohort consisted of workers employed 1 month or more between 1940 and 1979 at two Ohio shoe manufacturing plants. Vital status was ascertained through December 31, 1999. Seven thousand eight hundred twenty eight workers, contributing 300,777 person years, were available for analysis. An excess of lung cancer deaths persisted with additional years of follow-up (SMR = 1.36, 95% confidence interval (CI) = 1.19-1.54). Trend tests did not indicate a positive trend between lung cancer risk and duration of employment. Mortality from leukemia was not significantly elevated in the updated analysis. Results indicate a possible association between lung cancer mortality and exposure to chronic, low-levels of organic solvents. Although the strength of this conclusion was weakened by the lack of increasing lung cancer risk in relation to duration of employment, other studies have supported this association.
Keywords
Shoe-manufacturing; Workers; Mortality-data; Mortality-rates; Worker-health; Employees; Employee-health; Toluenes; Solvents; Lung-cancer; Cancer; Xylenes; Occupational-exposure; Occupational-health; Pulmonary-system-disorders; Employee-exposure; Risk-factors; Risk-analysis; Chronic-exposure; Organic-solvents
Contact
Everett J. Lehman, Industrywide Studies Branch, Division of Surveillance, Hazard Evaluations and Field Studies, The National Institute for Occupational Safety and Health, 4676 Columbia Parkway, R-13, Cincinnati, OH 45226
CODEN
AJIMD8
CAS No.
1330-20-7; 108-88-3
Publication Date
20060701
Document Type
Journal Article
Email Address
ELehman@cdc.gov
Fiscal Year
2006
NTIS Accession No.
NTIS Price
Issue of Publication
7
ISSN
0271-3586
NIOSH Division
DSHEFS
Source Name
American Journal of Industrial Medicine
State
OH
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