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Pesticide exposure, host susceptibility factors and risk of Parkinson's disease: an introduction to a work in progress.

Authors
Greenlee-AR; Burmester-JK; Hiner-BC
Source
WMJ 2002 Jan; 101(5):20-24
NIOSHTIC No.
20029622
Abstract
Linking exposures with bio­marker data may provide a clearer understanding of the mechanisms by which agrochemi­cal exposures influence the occurrence of PD and may assist with formulating strategies for reducing adverse health consequences for agricultural and other workers by policy design, education, and research. It may well be that the Parkinson phenotype is not the result of a single gene defect or of exposure to a single environmental toxin, but rather multiple potential combinations of genetic and environmental interactions. Ultimately the hope is that knowledge gained in studies such as this will allow clinicians to screen individuals for susceptibility genes, and advise them on specific environmental factors that need to be avoided in order to prevent the subsequent development of PD years later.
Keywords
Cell-biology; Cell-function; Cell-metabolism; Cell-morphology; Cellular-function; Cellular-structures; Pest-control; Pesticide-industry; Pesticide-residues; Pesticides; Pesticides-and-agricultural-chemicals
Contact
Marshfield Medical Research Foundation, 1000 N Oak Ave, Marshfield, WI 54449
Publication Date
20020101
Document Type
Journal Article
Email Address
greenla@mfldclin.edu
Funding Type
Cooperative Agreement
Fiscal Year
2002
NTIS Accession No.
NTIS Price
Identifying No.
Cooperative-Agreement-Number-U50-OH-007543
Issue of Publication
5
ISSN
1098-1861
Source Name
Wisconsin Medical Journal
State
WI
Performing Organization
Marshfield Clinic Research Foundation
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