Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

NIOSHTIC-2 Publications Search

Search Results

FEV6 as a surrogate for FVC in detecting airways obstruction and restriction in the workplace.

Authors
Akpinar-Elci-M; Fedan-KB; Enright-PL
Source
Eur Respir J 2006 Feb; 27(2):374-377
NIOSHTIC No.
20029574
Abstract
Compared with measurements of forced vital capacity (FVC), using the forced expiratory volume in six seconds (FEV(6)) reduces test time and frustration. It was hypothesised that using FEV(6) in the workplace setting would result in an acceptably low misclassification rate for detecting airways obstruction and spirometry-defined restriction when compared with using the traditional FVC. Experienced technicians from the National Institute for Occupational Safety and Health performed spirometry using dry rolling-seal spirometers as per American Thoracic Society guidelines in four workplace investigations. Airways obstruction was defined as an FEV(1)/FVC % below the lower limit of normal (LLN) using National Health and Nutrition Examination Survey III reference equations. Restriction was defined as an FVC below the LLN with a normal FEV(1)/FVC %. These "gold standard" definitions were compared with definitions based on FEV(6) (obstruction: FEV(1)/FEV(6) below the LLN; restriction: FEV(6) below the LLN with a normal FEV(1)/FEV(6)). The median (range) age of the 1,139 workers was 37 yrs (18-71 yrs) and 51.4% were male. A significantly high overall agreement was obtained between the two definitions. In conclusion, the current results confirm that forced expiratory volume in six seconds can be used as a surrogate for forced vital capacity in detecting airways obstruction and restriction in workers, although with some misclassification when compared to obtaining American Thoracic Society-acceptable manoeuvres of longer duration.
Keywords
Airway-obstruction; Airway-resistance; Spirometry; Workers; Worker-health; Demographic-characteristics; Age-factors; Age-groups; Sex-factors; Pulmonary-function; Pulmonary-function-tests; Author Keywords: Forced expiratory volume in six seconds; pulmonary function test; spirometry
Contact
M. Akpinar-Elci, NIOSH Division of Respiratory Diseases Studies, Field Studies Branch, Mail Stop H-2800, 1095 Willowdale Rd, Morgantown, WV 26505, USA
CODEN
ERJOEI
Publication Date
20060201
Document Type
Journal Article
Email Address
melci@cdc.gov
Fiscal Year
2006
NTIS Accession No.
NTIS Price
Issue of Publication
2
ISSN
0903-1936
NIOSH Division
DRDS
Source Name
European Respiratory Journal
State
WV
TOP