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Tumor necrosis factor-alpha.

Authors
Johnson-VJ
Source
Encyclopedic Reference of Immunotoxicology. Vohr HW, ed., New York: Springer-Verlag, 2005 Jun; :674-677
Link
NIOSHTIC No.
20029028
Abstract
Tumor necrosis factor-a (TNF-a) is a pleiotropic proinflammatory cytokine that mediates key roles in homeostasis, cell growth and proliferation, tissue damage, repair and chronic diseases. TNF-a production is induced by a plethora of stimuli including bacterial products, oxidative stress, other cytokines, and general tissue damage. As such, this cytokine has a central role in orchestrating many injury and disease states including immunotoxicity.
Keywords
Cell-growth; Tissue-disorders; Diseases; Chronic-degenerative-diseases; Bacteria; Bactericides; Immunotoxins
Contact
Toxicology and Molecular Biology Branch, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505, USA
Publication Date
20050601
Document Type
Book or book chapter
Editors
Vohr-HW
Fiscal Year
2005
NTIS Accession No.
NTIS Price
ISBN No.
3540441727
NIOSH Division
HELD
Source Name
Encyclopedic Reference of Immunotoxicology
State
WV
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