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Systemic inflammatory mediators contribute to widespread effects in work-related musculoskeletal disorders.

Authors
Barr-AE; Barbe-MF; Clark-BD
Source
Exerc Sport Sci Rev 2004 Oct; 32(4):135-142
NIOSHTIC No.
20028927
Abstract
Recent studies in a rat model have indicated that the pathophysiological mechanisms underlying development of work-related musculoskeletal disorders (WMSDs) include widespread inflammation and subsequent fibrosis at high levels of repetition and force. A systemic inflammatory component may affect tissues not directly involved in task performance, thereby contributing to widespread and puzzling symptoms that are often characteristic of patients with WMSDs.
Keywords
Animal-studies; Laboratory-animals; Muscular-disorders; Musculoskeletal-system-disorders; Muscle-tissue; Muscle-function; Repetitive-work; Ergonomics; Cumulative-trauma; Cumulative-trauma-disorders
Contact
Department of Work Environment, University of Massachusetts Lowell, Lowell, Massachusetts 01854
CODEN
ESSRB8
Publication Date
20041001
Document Type
Journal Article
Funding Type
Grant
Fiscal Year
2005
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-003970
Issue of Publication
4
ISSN
0091-6331
Source Name
Exercise and Sport Sciences Reviews
State
PA
Performing Organization
Temple University
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