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External contamination of antineoplastic drug vials.

Authors
Connor-TH
Source
Hosp Pharm Eur 2005 Nov; :52, 54
NIOSHTIC No.
20028624
Abstract
Healthcare workers are increasingly being exposed to antineoplastic and other hazardous drugs. Studies show that cleaning, in combination with covering the filled vial with a plastic film, can reduce external contamination on vials. Several factors have contributed to the potential for increase in exposure of healthcare workers to antineoplastic and other hazardous drugs. These include increasing numbers of patients with cancer and other chronic illnesses, the use of higher doses of drugs (made possible by strategies to reduce the toxic side-effects of the drugs), noncancer use of antineoplastic drugs and the development of other potent drugs, such as antiviral agents. Because it has been well documented over the past 20 years that healthcare workers, especially pharmacists and nurses, are exposed to these drugs in the workplace, government institutions and professional organisations around the world have developed guidelines for the safe handling of antineoplastic and other hazardous drugs. In the USA, the National Institute for Occupational Safety and Health (NIOSH)l recently published an alert that lists recommendations for the safe handling of all hazardous drugs, of which antineoplastic drugs are the major class. Others classes of hazardous drugs include some hormonal, immunosuppressive and antiviral agents, monoclonal antibodies and several miscellaneous drugs.
Keywords
Hazardous-materials; Drug-therapy; Drugs; Antineoplastic-agents; Health-care-facilities; Health-care-personnel
Publication Date
20051101
Document Type
Journal Article
Fiscal Year
2006
NTIS Accession No.
NTIS Price
ISSN
1477-1896
NIOSH Division
DART
Priority Area
Research Tools and Approaches: Exposure Assessment Methods
Source Name
Hospital Pharmacy Europe
State
OH
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