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Assessment of plutonium exposures for an epidemiological study of US nuclear workers.

Authors
Daniels-RD; Lodwick-CJ; Schubauer-Berigan-MK; Spitz-HB
Source
Radiat Prot Dosim 2006 Apr; 118(1):43-55
NIOSHTIC No.
20028143
Abstract
An ongoing case-control study evaluating the association between workplace external radiation exposures and leukaemia mortality required an assessment of internal plutonium exposures as a potential confounder. Of the study participants, 1092 were employed at four Department of Energy sites where plutonium-bearing materials were processed or stored. Exposures were assessed by first categorising exposure potentials based on available bioassay data, then estimating doses for workers in the highest categories using recent recommendations of the International Commission on Radiological Protection. Given the aetiology of leukaemia, equivalent dose to active bone marrow was chosen as the exposure variable. There were 556 workers each with at least one plutonium bioassay result, assigned to one of three evaluation categories. Dose estimates were made for 115 workers resulting in a collective equivalent dose of 2.1 person-Sv for 2822 exposure-years, compared with 29.8 person-Sv estimated from photon exposures. Modelling uncertainties were examined by comparison of results from independent analyses and by Monte Carlo simulation.
Keywords
Blood-disorders; Epidemiology; Radiation; Radiation-effects; Radiation-exposure; Cancer; Cancer-rates; Statistical-analysis
Contact
Division of Surveillance, Hazard Evaluations, and Field Studies (DSHEFS), National Institute for Occupational Safety and Health (NIOSH) 5555, Ridge Avenue, R-44 Cincinnati, OH 45213
CODEN
RPDODE
CAS No.
7440-07-5
Publication Date
20060401
Document Type
Journal Article
Fiscal Year
2006
NTIS Accession No.
NTIS Price
Issue of Publication
1
ISSN
0144-8420
NIOSH Division
DSHEFS
Source Name
Radiation Protection Dosimetry
State
OH
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