Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

NIOSHTIC-2 Publications Search

Search Results

Environmental health research in the post-genome era: new fields, new challenges, and new opportunities.

Authors
Bower-JJ; Shi-XL
Source
J Toxicol Environ Health, B 2005 Mar-Apr; 8(2):71-94
NIOSHTIC No.
20026267
Abstract
The human genome sequence provides researchers with a genetic framework to eventually understand the relationships of gene-environment interactions. This wealth of information has led to the birth of several related areas of research, including proteomics, functional genomics, pharmacogenomics, and toxicogenomics. Developing techniques such as DNA/protein microarrays, small-interfering RNA (siRNA) applications, two-dimensional gel electrophoresis, and mass spectrometry in conjunction with advanced analysis software and the availability of Internet databases offers a powerful set of tools to investigate an individual's response to specific stimuli. This review summarizes these emerging scientific fields and techniques focusing specifically on their applications to the complexities of gene-environment interactions and their potential role in environmental biosecurity.
Keywords
Biological-warfare-agents; Biological-weapons; Infectious-diseases; Genetics; Gene-mutation; Genetic-engineering
Contact
X. L. Shi, 1095 Willowdale Rd, MS 2015, Morgantown, WV 26505 USA
CODEN
JTECFR
Publication Date
20050301
Document Type
Journal Article
Fiscal Year
2005
NTIS Accession No.
NTIS Price
Issue of Publication
2
ISSN
1093-7404
NIOSH Division
HELD
Priority Area
Research Tools and Approaches: Cancer Research Methods
Source Name
Journal of Toxicology and Environmental Health, Part B: Critical Reviews
State
WV
TOP