Mortality trends in malignant neoplasm of the pleura - United States, 1979-1998.
Bang-KM; Pinheiro-GA; Wood-JM
Am J Epidemiol 2004 Jun; 159(11)(Suppl):S78
This presentation describes trends in mortality from pleural neoplasms (International Classification of Diseases, 9th Revision, Code 163) and identifies specific occupations and industries with elevated mortality associated with pleural neoplasms. The most common type of primary pleural cancer is malignant mesothelioma, which is frequently caused by exposure to asbestos fibers. We analyzed National Center for Health Statistics multiple cause-of-death data for the 20-year period 1979-1998, limited to U.S. residents aged 15 years and older. Annual mortality rates were calculated and age-adjusted to the U.S. Year 2000 Standard Population. A linear regression model was used for analyzing mortality rates trends over time. Proportionate mortality ratios (PMRs) by occupation and industry classifications, adjusted for age, sex, and race, were based on data restricted to certain states for which decedents' usual industry and occupational information was available since 1985. A total of 10,016 deaths during 1979-1998 were attributed to the pleural neoplasms. OveraIl age-adjusted mortality rates declined significantly (p<0.0001) from 2.8 per million in 1979 to 2.3 per million in 1998. The mortality rates for males and females both declined significantly: for females, from 1.4 to 0.9 (p<0.00 I) and for males, from 4.7 to 4.3 (p<0.05). PMRs for industries with elevated pleural neoplasm mortality included ship building, petroleum refining, and construction. Occupations with significantly elevated pleural neoplasm included insulation workers, plasters, and boilermakers. Much of this mortality likely resulted from historical exposure to asbestos fibers.
Respiratory-system-disorders; Pulmonary-system-disorders; Neoplasms; Mortality-data; Mortality-rates; Lung-cancer; Lung-disease; Lung-disorders; Statistical-analysis; Epidemiology; Construction-industry; Construction-workers; Insulation-workers; Insulation-industry; Petroleum-industry; Petroleum-refining; Petroleum-refineries; Shipyard-workers; Shipyard-industry; Shipbuilding-industry; Surveillance
American Journal of Epidemiology. Society for Epidemiologic Research (SER). Abstracts of the 37th Annual Meeting, Salt Lake City, Utah, June 15-18, 2004