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A risk analysis approach to selecting respiratory protection against airborne pathogens used for bioterrorism.

Authors
Nicas-M; Hubbard-A
Source
Am Ind Hyg Assoc J 2003 Jan/Feb; 64(1):95-101
NIOSHTIC No.
20024652
Abstract
The authors present a quantitative risk analysis approach to estimating infection risk due to airborne pathogens exhibiting relatively large infectious dose values. The method is applied to hypothetical scenarios involving airborne spores of Bacillus anthracis. The method combines the estimated parameters for exposure intensity, the pathogen dose-response relationship, and respirator penetration values (if respiratory protection is used). Because knowledge of the true parameter values will be uncertain, an uncertainty analysis is an essential part of the process. Given a specified value for acceptable infection risk, the method permits choosing a respirator that sufficiently reduces exposure to meet the acceptable risk criterion. A strength of the risk analysis approach is its transparency, in that the model structure and data inputs are explicitly identified. Further, risk analysis informs the expert judgment that must typically be applied in selecting respiratory protection against airborne pathogens.
Keywords
Statistical-analysis; Models; Respirators; Air-contamination; Respiration; Air-purification; Air-purifiers; Air-purifying-respirators; Personal-protective-equipment; Protective-equipment; Respiratory-protection; Respiratory-protective-equipment; Microorganisms; Bacterial-dusts
Contact
Center for Occupational and Environmental Health, School of Public Health, Room 140 Warren Hall, University of California, Berkeley, CA 94720-7360
CODEN
AIHAAP
Publication Date
20030101
Document Type
Journal Article
Email Address
mnicas@uclink4.berkeley.edu
Funding Amount
412603
Funding Type
Grant
Fiscal Year
2003
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-003570
Issue of Publication
1
ISSN
0002-8894
Priority Area
Research Tools and Approaches: Control Technology and Personal Protective Equipment
Source Name
American Industrial Hygiene Association Journal
State
CA
Performing Organization
University of California, Berkeley, California
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