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Cellular responses in exertion-induced skeletal muscle injury.

Authors
Stauber-WT; Smith-CA
Source
Mol Cell Biochem 1998 Feb; 179(1-2):189-196
NIOSHTIC No.
20024481
Abstract
Muscle injury is a common result of muscle exertion caused by overload and over-activity. In this presentation, an attempt was made to discuss models of muscle injury which involve exertion but not excessive strain, although most functional activities of the extremities require some eccentric muscle actions. Muscle injury is characterized by cellular and extracellular matrix responses which appear to be common to all types of muscle trauma -- even in the absence of bleeding. Using tenotomy and functional over-load of the rat hindlimb muscles as examples, illustrations of several of these responses are presented and discussed.
Keywords
Cellular-reactions; Musculoskeletal-system-disorders; Injuries; Skeletal-system-disorders; Skeletal-disorders; Muscle-stress; Models; Laboratory-animals; Animals; Animal-studies
Contact
W.T. Stauber, Department of Physiology, Robert C. Byrd Health Sciences Centre, West Virginia University, PO Box 9229, Morgantown, WV 26506-9229, USA
CODEN
MCBIB8
Publication Date
19980201
Document Type
Journal Article
Funding Amount
868663
Funding Type
Grant
Fiscal Year
1998
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-002918
Issue of Publication
1-2
ISSN
0300-8177
Priority Area
Disease and Injury: Musculoskeletal Disorders of the Upper Extremities
Source Name
Molecular and Cellular Biochemistry
State
WV
Performing Organization
West Virginia University, Morgantown, West Virginia
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