Paternal occupational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin and birthweight of offspring.
Lawson-CC; Schnorr-TM; Whelan-EA; Deddens-JA; Dankovic-DA; Piacitelli-LA; Sweeney-MH; Connally-LB
23rd International Symposium on Halogenated Environmental Organic Pollutants and POPs. Dioxin 2003. Vol. 64. Boston, MA: Dioxin 2003, :1-4
Agent Orange, a phenoxy herbicide, is a SO/50 mixture of the herbicides 2,4-D [(2,4-dichlorophenoxy)acetic acid] and 2,4,5-T [(2,4,5-trichlorophenoxy)acetic acid], which was contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). There have been few studies of paternal TCDD exposure and birthweight. The National Academy of Sciences (NAS) concluded there was insufficient or inadequate evidence to determine whether there is an association. We studied the pregnancy outcomes among wives of male workers highly exposed to chemicals contaminated with TCDD and among wives of non-exposed neighborhood referents that participated in a cross-sectional medical study. In the current paper we evaluate the association between paternal exposure to TCDD at the time of conception and birthweight of offspring.
Herbicides; Dioxins; Reproductive-hazards; Reproductive-effects; Epidemiology; Statistical-analysis
National Institute for Occupational Safety and Health, 4676 Columbia Pkwy, Cincinnati, OH 45226
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Conference/Symposia Proceedings; Abstract
23rd International Symposium on Halogenated Environmental Organic Pollutants and POPs. Dioxin 2003