A Random Walk Model of Stratum Corneum Diffusion.
Essential Stratum Corneum, Chapter 25, 2002 Jul :165-167
A mathematical model has been developed that is based on the molecular mechanism of diffusion and that explicitly incorporates the non-uniform structure of the stratum corneum. The model is used to predict permeability coefficients of chemicals based on their molecular weight (MW) and octanol-water partition coefficient (P).
Diffusion-analysis; Models; Mathematical-models; Chemical-properties; Simulation-methods
Book or book chapter
Marks-R; Leveque-J-L; Voegeli-R
Research Tools and Approaches: Exposure Assessment Methods
The Essential Stratum Corneum