We estimated self-reported mental health status and prevalence cognitive function problems among subjects with obstructive airway disease (OAD). We conducted telephone interviews with a national random sample of U.S. adults aged 55-75, enriched for subjects with OAD. Subjects classified as having no respiratory condition (NONE; n = 1585; 75%), asthma (ASTH; n = 128; 6%), or chronic obstructive l\U1g disease (COPD, emphysema chronic bronchitis, with or without concomitant asthma; COLD; n = 400; 19'/ Cognitive function was assessed with 3 self-report items concerning the freq. of problems with memory, confusion, or concentration. Reporting these problems at least "half the time" was considered to be a positive response. Multivariate logistic regression analyses controlling for age, sex, race/ethnicity, education, family income, smoking status, and presence of other common chronic health conditions were used to test differences in the frequency of cognitive dysfunction 22% of subjects with COLD reported having memory problems, compared to 13% of ASTH and 9% of NONE (p<.0001). 12% with COLD reported confusion (ASTH 5%, NONE 4%; p<.OOOI), and 18% reported problems concentrating (ASTH 12%, NONE 7%; p<.OOOI). Controlling for covariates, of problems with memory (OR=I.64, 95% CI 1.12,2.41), confusion (1.86[1.~ 3.15]), and concentration (2.09 [1.37, 3.18]) were elevated among those with COLD, compared to NONE. Individuals with COPD, emphysema and chronic bronchitis are at significant risk for cognitive function problems.
American Journal of Respiratory and Critical Care Medicine, 2002 International Conference, The American Thoracic Society, Atlanta Georgia, May 17-22, 2002