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Prevalence of depressive symptoms among adults with asthma.

Authors
Katz-PP; Eisner-MD; Yelin-EH; Earnest-G; San Pedro-M; San Pedro-M; Blanc-PD
Source
Am J Respir Crit Care Med 2002 Apr; 165(8)(Suppl):A434
NIOSHTIC No.
20022968
Abstract
The prevalence of depression is increased in certain chronic conditions but has not been well studied in asthma. We estimated the prevalence of depressive symptoms (DEP _SX) among a group of adults with asthma. We analyzed cross-sectional data from an ongoing study of adults with asthma surveyed by telephone (n=439). The CES-D (score range 0-60) was used to measure depressive symptoms. Individuals with DEP _SX (CES-D ~ 16) were identified. To identify independent risk factors for DEP _SX, we used multivariate regression analyses with the following independent variables: age, sex, race, education, # comorbid conditions, and severity of asthma score. A second set of analyses was conducted adding the Physical Component Score (PCS) of the SF-12, a measure of physical functioning, as an independent variable. 29% (n=129) had CES-D scores indicative of possible DEP _SX. Based on multivariate analyses, risk factors for DEP _SX were current smoking (OR=3.0 [95% CI 1.3,7.3]), more severe asthma (OR= 1.06 [1.02, 1.11] per I-pt increase), presence of?:2 comorbid conditions (2.4 [1.2, 4.7), female gender (1.8 [1.1, 3.2]), and age<45 years (2.0 [1.2, 3.3]). Adding PCS-12 improved the predictive model significantly (X2 for difference in models = 22.9, p<.OOI). In the model with PCS, only lower PCS (poorer function; OR=0.94 [.91, .96] per I-point decrease in PCS), current smoking (3.0 [1.2, 7.4]), and younger age (2.1 [1.2,3.6]) were significant predictors of DEP _SX. In this model, asthma severity was not significantly related to DEP _SX. DEP _SX appear to be significantly more common among adults with asthma than among the general population. Severity of asthma is a significant risk factor for DEP_SX, although the effect of severity is mediated by physical functioning. Smoking and younger age are also independent risk factors for DEP _SX. Health care providers should consider screening their patients with asthma for depression.
Keywords
Chronic-exposure; Respiratory-irritants; Respiratory-function-tests; Pulmonary-function; Pulmonary-system; Surveillance-programs; Age-factors; Racial-factors; Education; Smoking; Psychological-effects; Psychological-responses; Respiratory-system-disorders; Pulmonary-system-disorders
CODEN
AJCMED
Publication Date
20020401
Document Type
Abstract; Conference/Symposia Proceedings
Funding Amount
372,965
Funding Type
Grant
Fiscal Year
2002
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-003480
Issue of Publication
8
ISSN
1073-449X
Priority Area
Research Tools and Approaches: Social and Economic Consequences
Source Name
American Journal of Respiratory and Critical Care Medicine, 2002 International Conference, The American Thoracic Society, Atlanta Georgia, May 17-22, 2002
State
CA
Performing Organization
Cardiovascular Research Institute, The University of California, San Fransico California
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