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Prevalence of depressive symptoms among adults with asthma.

Katz-PP; Eisner-MD; Yelin-EH; Earnest-G; San Pedro-M; San Pedro-M; Blanc-PD
Am J Respir Crit Care Med 2002 Apr; 165(8)(Suppl):A434
The prevalence of depression is increased in certain chronic conditions but has not been well studied in asthma. We estimated the prevalence of depressive symptoms (DEP _SX) among a group of adults with asthma. We analyzed cross-sectional data from an ongoing study of adults with asthma surveyed by telephone (n=439). The CES-D (score range 0-60) was used to measure depressive symptoms. Individuals with DEP _SX (CES-D ~ 16) were identified. To identify independent risk factors for DEP _SX, we used multivariate regression analyses with the following independent variables: age, sex, race, education, # comorbid conditions, and severity of asthma score. A second set of analyses was conducted adding the Physical Component Score (PCS) of the SF-12, a measure of physical functioning, as an independent variable. 29% (n=129) had CES-D scores indicative of possible DEP _SX. Based on multivariate analyses, risk factors for DEP _SX were current smoking (OR=3.0 [95% CI 1.3,7.3]), more severe asthma (OR= 1.06 [1.02, 1.11] per I-pt increase), presence of?:2 comorbid conditions (2.4 [1.2, 4.7), female gender (1.8 [1.1, 3.2]), and age<45 years (2.0 [1.2, 3.3]). Adding PCS-12 improved the predictive model significantly (X2 for difference in models = 22.9, p<.OOI). In the model with PCS, only lower PCS (poorer function; OR=0.94 [.91, .96] per I-point decrease in PCS), current smoking (3.0 [1.2, 7.4]), and younger age (2.1 [1.2,3.6]) were significant predictors of DEP _SX. In this model, asthma severity was not significantly related to DEP _SX. DEP _SX appear to be significantly more common among adults with asthma than among the general population. Severity of asthma is a significant risk factor for DEP_SX, although the effect of severity is mediated by physical functioning. Smoking and younger age are also independent risk factors for DEP _SX. Health care providers should consider screening their patients with asthma for depression.
Chronic-exposure; Respiratory-irritants; Respiratory-function-tests; Pulmonary-function; Pulmonary-system; Surveillance-programs; Age-factors; Racial-factors; Education; Smoking; Psychological-effects; Psychological-responses; Respiratory-system-disorders; Pulmonary-system-disorders
Publication Date
Document Type
Abstract; Conference/Symposia Proceedings
Funding Amount
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Fiscal Year
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NTIS Price
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Issue of Publication
Priority Area
Research Tools and Approaches: Social and Economic Consequences
Source Name
American Journal of Respiratory and Critical Care Medicine, 2002 International Conference, The American Thoracic Society, Atlanta Georgia, May 17-22, 2002
Performing Organization
Cardiovascular Research Institute, The University of California, San Fransico California