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Urinary reproductive hormone level differences between African American and Caucasian women of reproductive age.

Authors
Reutman-S; LeMasters-G; Kesner-J; Shukla-R; Krieg-E; Knecht-E; Lockey-J
Source
Fertil Steril 2002 Aug; 78(2):383-391
NIOSHTIC No.
20022421
Abstract
To compare urinary levels of reproductive hormones in African American and Caucasian women. Cross-sectional study. Ten United States Air Force (USAF) bases. African American (n = 33) and Caucasian (n = 65) women of reproductive age from a larger study of USAF women (n = 170). None. Urinary endocrine end points: follicular luteinizing hormone (LH), preovulatory LH, level of LH surge peak, early follicular follicle stimulating hormone (FSH), follicular LH:FSH ratio, midluteal FSH, FSH rise before menses, early follicular estrone 3-glucuronide (E(1)3G), midfollicular E(1)3G, periovulatory E(1)3G peak, midluteal E(1)3G, early follicular pregnanediol 3-glucuronide (Pd3G), follicular Pd3G, rate of periovulatory Pd3G increase, E(1)3G:Pd3G on the day of luteal transition, slope of E(1)3G:Pd3G, and midluteal Pd3G. Relative to Caucasians, African American women had significantly lower follicular phase LH:FSH ratios (mean +/- SD: 0.7 +/- 0.4 vs. 1.0 +/- 0.6), lower follicular phase Pd3G levels (1.0 +/- 0.5 vs. 1.2 +/- 0.8 microg/mg creatinine), and lower rates of periovulatory Pd3G increase (0.5 +/- 0.7 vs. 1.0 +/- 1.2 microg/mg creatinine). Findings of this analysis should be considered preliminary evidence of racial differences in hormone levels. Future studies are needed to determine whether these differences have clinical significance.
Keywords
Urinalysis; Urine-chemistry; Endocrine-system; Reproductive-system; Hormones; Hormone-activity; Racial-factors; Military-personnel; Estrogenic-hormones; Epidemiology
Contact
Susan Reutman, 104 Park Avenue, Elsmere, KY 41018
CODEN
FESTAS
Publication Date
20020801
Document Type
Journal Article
Email Address
ereutman@hotmail.com
Fiscal Year
2002
NTIS Accession No.
NTIS Price
Issue of Publication
2
ISSN
0015-0282
NIOSH Division
DART
Priority Area
Disease and Injury: Fertility and Pregnancy Abnormalities
Source Name
Fertility and Sterility
State
OH
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