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Development of a filter assembly to match the deposition of ultrafine aerosol in the lung: a pilot study with beryllium.

Authors
McCawley-M; Martin-S; Moyer-E; Berakis-M; Hornsby-Myers-J; Kent-M
Source
Ann Occup Hyg, Inhaled Particles IX, 2002 Dec; 46(Suppl 1):215-218
NIOSHTIC No.
20022268
Abstract
A new criterion has previously been proposed for assessing inhalation risk from ultrafine aerosols. This deposited submicrometer particulate (DSP) criterion matches the lung deposition curve for aerosols with a size of <1 um. A method for matching the DSP criterion using racketched polycarbonate filters has been described in the literature, but the sampling results must be adjusted by a correction factor to match the DSP curve. A new design that matches the criterion without the need for any correction factors and has been used with a real-time particle counter to measure processes in the beryllium industry where data suggest that the ultrafine "0.1 microm) fraction of beryllium might be an important metric for predicting disease.
Keywords
Filters; Aerosols; Lung; Beryllium-compounds; Inhalation-studies; Sampling; Diseases; Particulate-dust; Particulates; Dusts; Dust-inhalation; Nanotechnology; Author Keywords: ultrafine particles; beryllium; lung deposition
Contact
M. McCawley, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505, USA
CODEN
AOHYA3
Publication Date
20021201
Document Type
Journal Article
Editors
Ogden-T; Donaldson-K; Cherry-N
Fiscal Year
2003
NTIS Accession No.
NTIS Price
ISSN
0003-4878
NIOSH Division
DRDS
Priority Area
Research Tools and Approaches: Exposure Assessment Methods
Source Name
Annals of Occupational Hygiene, Inhaled Particles IX
State
WV; OH
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