Development of a filter assembly to match the deposition of ultrafine aerosol in the lung: a pilot study with beryllium.
McCawley-M; Martin-S; Moyer-E; Berakis-M; Hornsby-Myers-J; Kent-M
Ann Occup Hyg, Inhaled Particles IX, 2002 Dec; 46(Suppl 1):215-218
A new criterion has previously been proposed for assessing inhalation risk from ultrafine aerosols. This deposited submicrometer particulate (DSP) criterion matches the lung deposition curve for aerosols with a size of <1 um. A method for matching the DSP criterion using racketched polycarbonate filters has been described in the literature, but the sampling results must be adjusted by a correction factor to match the DSP curve. A new design that matches the criterion without the need for any correction factors and has been used with a real-time particle counter to measure processes in the beryllium industry where data suggest that the ultrafine "0.1 microm) fraction of beryllium might be an important metric for predicting disease.
Filters; Aerosols; Lung; Beryllium-compounds; Inhalation-studies; Sampling; Diseases; Particulate-dust; Particulates; Dusts; Dust-inhalation; Nanotechnology;
Author Keywords: ultrafine particles; beryllium; lung deposition
M. McCawley, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505, USA
Ogden-T; Donaldson-K; Cherry-N
Research Tools and Approaches: Exposure Assessment Methods
Annals of Occupational Hygiene, Inhaled Particles IX