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Ethnicity and unprovoked hypokalemia in the atherosclerosis risk in communities study.

Authors
Andrew-ME; Jones-DW; Wofford-MR; Wyatt-SB; Schreiner-PJ; Brown-CA; Young-DB; Taylor-HA
Source
Am J Hyper 2002 Jul; 15(7) :594-549
NIOSHTIC No.
20022191
Abstract
BACKGROUND: Hypertension is more prevalent in the African American population when compared with the European American population in the United States. Unprovoked hypokalemia may lead to hypertension and is associated with several forms of recognized secondary hypertension. METHODS: We investigated the association of ethnicity with unprovoked hypokalemia in the second Atherosclerosis Risk in Communities (ARIC) study examination. Hypokalemia was defined as serum potassium <3.5 mmol/L. RESULTS: A statistically significant association was detected between ethnicity and unprovoked hypokalemia (odds ratio = 5.3; 95% confidence interval = 3.6, 7.7) with unprovoked hypokalemia more prevalent in African Americans both before and after adjustment for important covariates. The unadjusted prevalence for unprovoked hypokalemia was 2.6% for African Americans and 0.5% for European Americans. CONCLUSIONS: We found that the prevalence of unprovoked hypokalemia for African Americans in the ARIC cohort was more than five times that for European Americans. These data suggest that an increased awareness of hypokalemia and its etiology may be indicated for African Americans.
Keywords
Potassium-compounds; Ethanols; Dietary-effects; Blood-pressure; Cardiovascular-function; Blood-pressure; Mortality-rates; Blood-analysis; Author Keywords: Hypokalemia; ethnicity; potassium; hypertension; ARIC
Contact
Health Effects Laboratory Division, National Institute for Occupational Safety and Health, CDC, 1095 Willowdale Road, M.S. 4020, Morgantown, WV 26505
CODEN
AJHYE6
Publication Date
20020701
Document Type
Journal Article
Email Address
mandrew@cdc.gov
Fiscal Year
2002
NTIS Accession No.
NTIS Price
Issue of Publication
7
ISSN
0895-7061
NIOSH Division
HELD
Priority Area
Other Occupational Concerns; Cardiovascular Disease
Source Name
American Journal of Hypertension
State
WV
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