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Mortality in dry-cleaning workers: an update.

Authors
Ruder-A; Ward-E; Brown-D
Source
Am J Ind Med 2001 Feb; 39(2):121-132
NIOSHTIC No.
20021854
Abstract
A cohort of 1,708 dry-cleaning workers identified from union records was exposed to perchloroethylene (PCE), a known animal carcinogen and probable human carcinogen, for at least 1 year before 1960. Many workers also had exposure to Stoddard solvent, a petroleum-based dry-cleaning solvent. Vital status was updated through 1996 and life table analyses conducted. The cohort had excess cancer mortality (271 deaths, standardized mortality ratio [SMR] 1.25, 95% confidence interval [CI] 1.11-1.41). Elevated SMRs for tongue, bladder, esophagus, intestine, lung, and cervical cancer, pneumonia, and diseases of the stomach and duodenum were statistically significant. The current study confirms findings of prior updates and other studies that dry-cleaning workers have excess cancer mortality at several sites. Although important lifestyle and socioeconomic risk factors exist for both cervical and esophageal cancer mortality, excesses of these sites in the PCE only subcohort and among workers with longer duration of PCE exposure suggest an association with PCE exposure.
Keywords
Dry-cleaning-industry; Workers; Mortality-rates; Mortality-data; Solvents; Occupational-exposure; Cancer; Dry-cleaning-solvents; Carcinogens; Worker-health
Contact
Avima M. Ruder, Mailstop R-16, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, Cincinnati, OH 45226
CODEN
AJIMD8
CAS No.
127-18-4
Publication Date
20010201
Document Type
Journal Article
Email Address
amr2@cdc.gov
Fiscal Year
2001
NTIS Accession No.
NTIS Price
Issue of Publication
2
ISSN
0271-3586
NIOSH Division
DSHEFS
Source Name
American Journal of Industrial Medicine
State
OH; NC
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