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Neurophysiological function in farm workers exposed to organophosphate pesticides.

Authors
Engel-LS; Keifer-MC; Checkoway-H; Robinson-LR; Vaughan-TL
Source
Arch Environ Health 1998 Jan; 53(1):7-14
NIOSHTIC No.
20001019
Abstract
To investigate neurophysiological effects of low-level exposure to foliar organophosphate residues during one season among agricultural workers, the authors performed a cross-sectional study of 67 Hispanic farm workers and 68 age-, gender-, ethnicity-, and education-matched reference subjects. The neurophysiological examination included sensory and motor nerve conduction and neuromuscular junction testing. Erythrocyte cholinesterase activity was measured at the time of examination. No statistically significant neurophysiological differences between the exposed and reference groups were observed. Farm workers and reference subjects had similar sensory nerve latency and amplitude (sural), motor nerve conduction velocity (ulnar), and neuromuscular junction function (ulnar). No relationship between duration of exposure during the season and electrophysiological measures of nerve function was found. Exposure of farm workers to the low levels of organophosphate pesticides during one season experienced by farm workers in this study was not associated with impaired peripheral neurophysiological function.
Keywords
Pesticides-and-agricultural-chemicals; Pesticides; Neurophysiological-effects; Neuromuscular-system-disorders; Neurophysiology; Neurotoxic-effects; Organo-phosphorus-pesticides; Agricultural-workers; Agricultural-chemicals; Farmers; Neurological-reactions; Neurological-system; Neuromotor-system-disorders; Neurotoxins; Nerve-function; Workers; Worker-health
Contact
Department of Epidemiology, University of Washington, Seattle, Washington
CODEN
AEHLAU
Publication Date
19980101
Document Type
Journal Article
Funding Amount
161395
Funding Type
Grant
Fiscal Year
1998
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-K01-OH-00133
Issue of Publication
1
ISSN
0003-9896
Priority Area
Work Environment And Workforce: Special Populations
Source Name
Archives of Environmental Health
State
WA
Performing Organization
Department of Medicine & Environmental Health, school of Medicine, University of Washington
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