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Criteria for a recommended standard: occupational exposure to glycidyl ethers.

Authors
NIOSH
Source
NIOSH 1978 Jun; :1-197
NIOSHTIC No.
20000330
Abstract
Glycidyl ethers are characterized by the presence of a three-carbon chain with an epoxide group and an ether linkage. This recommended standard applies to monoglycidyl ethers and diglycidyl ethers that contain an alkyl group, an aromatic group, or a moiety of the structure -(RO)n-R'. It does not include any halogenated compounds or polymerized forms. Most of the glycidyl ethers are liquids but some are solids. The most common use of these compounds is as reactive diluents in epoxy resins. Toxicologic data concerning these compounds are scarce, but those available show that glycidyl ethers are primary skin and eye irritants and that they are potential skin sensitizing agents. Some data suggest that di(2,3-epoxypropyl) ether should be regarded as a potential occupational carcinogen and that n-butyl glycidyl ether is a mammalian mutagen. Some glycidyl ethers have also produced cytotoxic effects in animals.
Keywords
Hazardous-materials; Industrial-medicine; Exposure-levels; Standards; Industrial-hygiene; Thresholds; Occupational-safety; Air-sampling; Maximum-permissible-concentrations; Mutagenesis; Teratogenesis; NIOSH-Criteria-Document
CAS No.
106-92-3; 4016-14-2; 122-60-1; 2426-08-6; 2238-07-5
Publication Date
19780601
Document Type
Numbered Publication; Criteria Document
Fiscal Year
1978
NTIS Accession No.
PB81-229700
NTIS Price
A11
Identifying No.
(NIOSH) 78-166
NIOSH Division
DCDSD
Source Name
National Institute for Occupational Safety and Health
State
MD
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