Urine vanadium concentrations in workers overhauling an oil-fired boiler.
Hauser-R; Elreedy-S; Ryan-PB; Christiani-DC
Am J Ind Med 1998 Jan; 33(1):55-60
The range of urinary levels of vanadium (7440622) in oil fired furnace repair workers and the timing of urine sampling for optimal determination of urinary vanadium as a biomarker of exposure to fuel oil ash was studied. Vanadium was measured in urine samples obtained from 20 male boilermakers prior to the start of a shift and immediately after a shift and occupational exposure to inhalable particulates was determined by air sampling. A mean of 1.15 milligrams/gram vanadium was measured in preshift samples; a mean of 1.44 milligrams/gram was measured in postshift samples. Air vanadium levels ranged from 0.36 to 32.19 micrograms/cubic meter. Urinary vanadium was significantly higher in postshift than in preshift samples in workers on the first day back to work following 17 days off. Urinary vanadium levels were not significantly different when measured 38 hours after the end of the shift without additional exposure. The authors conclude that vanadium is rapidly cleared on the first day of work, followed by a slower phase of clearance. Spearman correlations suggested that preshift urine samples are preferable to postshift samples for across shift biomonitoring of occupational vanadium exposure.
NIOSH-Publication; NIOSH-Cooperative-Agreement; Pulmonary-system-disorders; Vanadium-compounds; Urinalysis; Biological-monitoring; Bioassays; Occupational-exposure; Vanadium-dust; Boiler-furnaces;
Author Keywords: urine vanadium; biological monitoring; fuel oil ash
American Journal of Industrial Medicine
Harvard School of Public Health