This document provided an overview of National Occupational Research Agenda (NORA) and the progress made in the first year. The NORA Liaison Committee has worked with NIOSH to begin the transformation from a concept to a reality. Altogether, 20 NORA teams have been established including NIOSH staff and partners from academia, labor, industry, professional organizations, and other Government agencies. Increases in investment in NORA research areas has been observed. Twenty one research priorities were identified, including allergic and irritant dermatitis, asthma and chronic obstructive pulmonary disease, fertility and pregnancy abnormalities, hearing loss, infectious diseases, low back disorders, musculoskeletal disorders of the upper extremities, traumatic injuries, emerging technologies, indoor environment, mixed exposures, organization of work, special populations at risk, cancer research methods, control technology and personal protective equipment, exposure assessment methods, health services research, intervention effectiveness research, risk assessment methods, social and economic consequences of workplace illness and injury, and surveillance research methods. The success of NORA can be measured by NIOSH's research investment, other Federal agencies investments, funding of grant applications in NORA priority areas, research literature and prevention and intervention activities arising out of NORA. In this one year NORA has been recognized as a model for public/private partnerships.