Strategies for Safe Use of Chemicals in Animal Research.
Working Safely with Research Animals, Proceedings of the 4th National Symposium on Biosafety, Atlanta, Georgia, January 27-31, 1996 1996 Jan:71-75
A brief survey of chemical use in the animal facility was presented. While animal facilities are less dangerous for chemical exposure than manufacturing and industrial facilities, when exposure occurred, the routes for interaction with the body included inhalation, dermal, ocular, oral, and iatrogenic. The respiratory and dermal routes were most affected in those involved in animal research. Some chemicals were acutely toxic, carcinogenic, mutagenic, teratogens, or allergens. Chemicals commonly used in animal facilities were pharmaceuticals, anesthetics, cleaning compounds, pesticides, and fixatives. Key areas of knowledge relevant to using chemicals safely in animal facilities included having an accurate inventory of all chemicals present; knowing the risk each poses to workers; and knowing how chemicals are used. Minimizing chemical exposure required using personal protective equipment and engineering controls. The way to approach safety was shaped by the goal chosen. A better paradigm than having a healthy workplace was having healthy workers. The authors conclude that the strategy for the safe use of chemicals in the animal facility required a diligent effort to apply professional judgment in a better paradigm.
Laboratory-animals; Health-survey; Chemical-manufacturing-industry; Chemical-processing; Inhalants; Skin-exposure; Occupational-exposure;
Working Safely with Research Animals, Proceedings of the 4th National Symposium on Biosafety, Atlanta, Georgia, January 27-31, 1996