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Interactions of radiofrequency radiation on 2-methoxyethanol teratogenicity in rats.

Authors
Nelson-BK; Conover-DL; Shaw-PB; Snyder-DL; Edwards-RM
Source
J Appl Toxicol 1997 Jan; 17(1):31-39
NIOSHTIC No.
00236153
Abstract
The interactive effects of radiofrequency (RF) radiation and 2- methoxyethanol (109864) (2-ME) exposure were observed in rats. Mated female CD-Sprague-Dawley-rats were exposed to RF radiation at a frequency of 10 megahertz (MHz) for up to 30 minutes and gavaged with 2-ME at concentrations ranging from 0 to 140mg/kg on gestational day 13. On day 20, the dams were killed and the fetuses were removed and analyzed for external and skeletal malformations. Dose related developmental toxicity was seen for 2-ME, either with or without RF radiation. The dose effect curve of 2-ME was altered by concurrent RF radiation exposure. The authors conclude that, when developing exposure guidelines and intervention strategies, the potential combined effects of exposure should be included in the assessments.
Keywords
NIOSH-Author; Laboratory-animals; Toxic-effects; Radiation-exposure; Reproductive-effects; Prenatal-exposure; Ethylenic-alcohols; Dose-response
CODEN
JJATDK
CAS No.
109-86-4
Publication Date
19970101
Document Type
Journal Article
Fiscal Year
1997
NTIS Accession No.
NTIS Price
Issue of Publication
1
ISSN
0260-437X
NIOSH Division
DBBS
Source Name
Journal of Applied Toxicology
State
OH
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