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Occupational hazard assessment of trinitrotoluene. Interim report.

Authors
Anonymous
Source
JRB Associates, Inc., McLean, Virginia 1980 Mar; :1-102
Link
NIOSHTIC No.
00235391
Abstract
The biological effects of exposure to trinitrotoluene (118967) (TNT) were discussed, along with the evaluation and control of exposure. Exposure to TNT can occur during the production, handling, and packing operations. TNT has been used in textile dyeing and as the principal raw material in manufacturing phloroglucinol (108736), used in black on white photocopying. Metabolism follows one or more of three general pathways: nitroreduction, oxidation of an allyl group when present, and direct hydroxylation of the aromatic ring. Fatalities have resulted from aplastic anemia, toxic hepatitis, and other factors. Neurologic effects were noted which included excessive perspiration, acrocyanosis, transient eruption of red skin patches, unstable pulse and arterial pressure, and central nervous system disorders including headaches, dizziness, irritability, poor memory, and disturbed sleep. Ocular effects were described as well as dermal effects. Results of epidemiologic studies were highlighted. Sampling and analytical methods were reviewed, and methods for controlling safety hazards and health hazards associated with TNT were considered.
Keywords
NIOSH-Contract; Contract-210-78-0017; Nitro-compounds; Liver-damage; Toluenes; Skin-disorders; Neurotoxic-effects; Toxic-effects; Skin-exposure; Nervous-system-disorders; Occupational-exposure; Industrial-hygiene
CAS No.
118-96-7; 108-73-6
Publication Date
19800321
Document Type
Final Contract Report
Funding Type
Contract
Fiscal Year
1980
NTIS Accession No.
PB97-151732
NTIS Price
A07
Identifying No.
Contract-210-78-0017
Priority Area
Neurotoxic-effects
Source Name
JRB Associates, Inc., McLean, Virginia
State
VA
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