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Lung disease in Chinese textile workers.

Authors
Christiani-DC
Source
Department of Environmental Health, School of Public Health, Harvard University, Boston, Massachusetts 1995 Oct; :1-21
Link
NIOSHTIC No.
00235386
Abstract
The relationship between long term exposure to cotton dust and associated gram negative bacterial endotoxin on lung function was investigated in an 11 year prospective study of cotton textile workers in Shanghai, China. Workers at a nearby silk thread manufacturing mill served as a referent population. The cotton workers had a larger loss of lung function as measured by forced expiratory volume in 1 second (FEV1) during the first 5 years of the study than in the second 6 years. The average decline among silk workers was slightly higher in the first period, but was more consistent. Cumulative dust but not endotoxin was associated with an 11 year loss of FEV1 after adjustment for appropriate confounders when cumulative exposure to dust and endotoxin were estimated and retired workers included in the testing. No evidence was found for interaction between smoking and cumulative dust or cumulative endotoxin exposure in these models. Results suggest that the cotton dust is a relatively potent cause of chronic airflow limitation independent of associated endotoxins.
Keywords
NIOSH-Grant; Pulmonary-system-disorders; Textiles-industry; Cotton-dust; Cotton-mill-workers; Plant-dusts; Dust-exposure; Pulmonary-function; Occupational-exposure
Contact
Environmental Sci & Physiology Harvard School of Public Hlth 665 Huntington Ave Boston, MA 02115
Publication Date
19951020
Document Type
Final Grant Report
Funding Amount
1348724
Funding Type
Grant
Fiscal Year
1996
NTIS Accession No.
PB97-151773
NTIS Price
A03
Identifying No.
Grant-Number-R01-OH-002421
NIOSH Division
OEP
Source Name
Department of Environmental Health, School of Public Health, Harvard University, Boston, Massachusetts
State
MA
Performing Organization
Harvard University
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