Longitudinal and cross-sectional analyses of lung function in steelworkers.
Wang-ML; McCabe-L; Hankinson-JL; Shamssain-MH; Gunel-E; Lapp-NL; Banks-DE
Am J Respir Crit Care Med 1996 Jun; 153(6):1907-1913
Lung function in steelworkers was examined in a longitudinal and cross sectional analysis. The medical records of 1,171 employees were randomly chosen and reviewed for spirometry data as well as for demographic data; in all, the records of 475 steelworkers who had at least three spirometry tests between 1982 and 1991 were studied. The group included 451 white men and 24 black men. A relationship was found between smoking, aging, being overweight, excessive weight gain, and dust exposure with a lower level and a steeper slope of decline of pulmonary function. Forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), and FEV1/FVC% displayed a loss of baseline due to dust exposure of 9.3 milliliters (ml), 6.4ml and 0.1% per year of employment in a dusty area. However, the association between dust exposure and longitudinal decline of lung function was weak. There was a strong relationship between weight gain and longitudinal decline of FEV1 and FVC. A FEV1 decline of 4.7ml per pound per year and a FVC loss of 6.3ml was due to weight gain. The authors suggest that weight gain is an important factor for longitudinal lung function decline.
NIOSH-Publication; NIOSH-Cooperative-Agreement; Pulmonary-system-disorders; Epidemiology; Lung-function; Occupational-exposure; Dust-exposure; Body-weight; Pulmonary-function-tests; Humans
Mei-lin Wang, M.D., Research Assistant Professor of Medicine, Section of Pulmonary and Critical Care Medicine, West Virginia University School of Medicine, Morgantown, WV 26506-9166
American Journal of Respiratory and Critical Care Medicine
Center to Protect Workers' Rights