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Functional changes in central auditory pathways resulting from cochlear diseases.

Authors
Salvi-RJ; Henderson-D; Boettcher-FA; Powers-NL
Source
Central Auditory Processing: A Transdisciplinary View. Katz J, Stecker NA, Henderson D, eds., St. Louis, MO: Mosby Year Book, 1992 Sep; :47-60
Link
NIOSHTIC No.
00232611
Abstract
This report reviewed some of the functional changes occurring in the central auditory system of individuals who suffer from sensorineural hearing loss. The authors reviewed the enhancement of evoked potential amplitude with peripheral loss, the altering of the normal balance between the excitatory and inhibitory inputs that impinge on individual neurons in the central auditory pathway, and tonotopic reorganization in the auditory cortex. Current knowledge has forced a change from the traditional view of the central auditory system to one which allows that functional changes may occur in the central auditory system as a result of cochlear damage. Such damage causes the tonotopic organization of the auditory cortex to undergo significant rearrangement in adult animals. The over representation of neurons in the inferior colliculus with characteristic frequencies bordering the hearing loss may possibly promote the abnormally large amplitude evoked responses observed in many studies. If the evoked response amplitude enhancement results from tonotopic reorganization, it would suggest that the tonotopic reorganization occurs as far peripherally as the cochlear nucleus. Clinical and practical significance which may be ascribed to tonotopic reorganization and evoked response amplitude enhancement may include loudness recruitment and loudness intolerance, and possibly tinnitus.
Keywords
NIOSH-Grant; Noise-induced-hearing-loss; Industrial-noise; Laboratory-animals; Sensory-thresholds
Publication Date
19920901
Document Type
Book or book chapter;
Editors
Katz-J; Stecker-NA; Henderson-D
Funding Amount
2388849
Funding Type
Grant;
Fiscal Year
1992
NTIS Accession No.
NTIS Price
ISBN No.
1556643721
Identifying No.
Grant-Number-R01-OH-001152
Priority Area
Noise-induced-hearing-loss
Source Name
Central Auditory Processing: A Transdisciplinary View
State
NY
Performing Organization
State University of New York, Buffalo, New York
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