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The genetics of noise-induced hearing loss.

Authors
Davis-RR; Erway-LC; Cortopassi-G
Source
Sixth US-Finnish Joint Symposium on Occupational Health and Safety, People and Work, Proceedings of the Sixth FIOH-NIOSH Joint Symposium on Occupational Health and Safety, 8-10 August 1995, Espoo, Finland. People and Work - Research Reports 3. H. Nordman, J. Starck, A. Tossavainen, E. Viikari-Juntura, eds. Helsinki, Finland: Finnish Institute of Occupational Health; 1995 Aug; :31-34
Link
NIOSHTIC No.
00229718
Abstract
The differences in susceptibility to noise induced hearing loss (NIHL) which may be attributed to genetic factors were discussed. The use of genetic, inbred strains of mice as models for hearing studies was explained; the advantages of using a murine model included small size, easy breeding, short time between generations, production of identical offspring, and the fact that much of their genome has been mapped for homologies with the human genome. The use of various strains in studies of genes and age related or noise related hearing loss was described. Studies were underway to characterize the effect of noise on the ahl-1 genotypes. Human implications associated with these studies were discussed. The authors conclude that by identifying human genes responsible for noise sensitivity, it may be possible to warn workers prior to noise exposure and to prevent NIHL. Workers who may have particular sensitivity to NIHL would be provided with higher levels of hearing protection or by working shorter amounts of time in noisy situations.
Keywords
Genetic-factors; Noise-exposure; Risk-factors; Laboratory-animals; Noise-induced-hearing-loss; Age-factors; Hearing-loss; Genetics
Publication Date
19950801
Document Type
Conference/Symposia Proceedings
Editors
Nordman-H; Starck-J; Tossavainen-A; Viikari-Juntura-E
Fiscal Year
1995
NTIS Accession No.
NTIS Price
ISBN No.
9789518021028
ISSN
1237-6183
NIOSH Division
DBBS
Priority Area
Noise-induced-hearing-loss
Source Name
Sixth US-Finnish Joint Symposium on Occupational Health and Safety, People and Work, Proceedings of the Sixth FIOH-NIOSH Joint Symposium on Occupational Health and Safety, 8-10 August 1995, Espoo, Finland. People and Work - Research Reports 3
State
OH; CA
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